I have the same issue with the glass tailgate. It shuts really easily (compared to reports I've heard from others), but the weatherstrip squeaks quite badly when driving over broken pavement.
I did a little research on the internet and what dbwill says is spot on. A professional grade weathersrip lubricant should be a big help. The key ingredient is Krytox - a teflon based lubricant produced by Du Pont. There are a couple of good sources for this:
- GM sells a weatherstrip lubricant that has Krytox as its main ingredient. It's a liquid formulation with an applicator built into the bottle. It dries within a minute or so - no lasting sticky residue. Part number is 3634770, and you can order it directly from www.gmpartsdirect.com.
- Second option is a spray-on aerosol version made by Loctite. It also dries rapidly on contact. Part number is 30138 - Krytox RFE Advanced PTFE Dry Lubricant. You can order a can online at www.weldwarehouse.com.
I've ordered the Loctite version (seemed like a better value). I'll report back when it arrives and I've had a chance to try it out.
PS: The prices for these products may seem high ($30+ for a small quantity), but everything I've read says they are worth every penny - they really work (unlike the cheap silicone based lubricants you can get from the likes of NAPA) and are very long lasting in their effect.