Specific to run-flats.. in my opinion.. they are evil. With no spare, maybe not, but day-to-day living with them paired with [legally] un-repatchable design (though most shops will attempt) was a giant bummer when I had my MINI. They ride horribly, are very expensive to replace and in my experience, were more prone to damage. I'd rather have normal tires with a spare. Without... well, that's the way it is, but I'd prefer a doughnut in emergencies.