My 2009 ran good for 168,000 miles until one day it dropped a cylinder when heading to work. I drove about 3 miles and it would shudder and shake, no power, etc. When I shut it off and restarted it, the CEL went off and it ran for another 3 miles or so. eventually the CEL wouldn't g out but I could reset it with my scangauge II. I got a compression tester and found cylinder
#1 had 65 PSI and the others had 155 and 160. even after finding that, it would run OK for a bit before the computer would shut down the cylinder. Exhaust was replaced at just over 100K miles.
Car was driven roughly 100 miles a day on highways and back roads so it didn't have any carbon built up. Adding oil to the cylinder did not change the reading so I assume it was a burned valve. Regular oil changes with Mobil1, premium gas and filter changes at recommended intervals, same with plugs, etc.
The computers on these cars do a big job of monitoring a massive amount of sensors, they will detect a problem before you can feel it.